The impact of elite endurance activity on cardiac remodelling in asians: an echocardiographic case control study

Abstract Background Prolonged endurance training results in physiological changes to elite athletes' hearts. These include thickened left ventricular (LV) walls and dilated right ventricles that may overlap with those from pathological conditions such as hypertrophic cardiomyopathy, cardiomyopathy arrhythmogenic cardiomyopathy. While reference ranges for black white athletes have been published facilitate differentiation of physiology pathology, data on Asian remains scarce. With increasing representation international sport, it is important ascertain the extent cardiac remodelling athletes. Purpose This study aimed compare echocardiographic parameters (EAs) non-endurance controls describe this population Methods Consecutive engaging sport were identified Singapore Sports Cardiology Registry January October 2018. Controls obtained 3 sources: (a) skill-based Registry, (b) healthy non-athletic volunteers a national atrial fibrillation registry, (c) heart failure registry. All participants underwent resting two-dimensional, M-mode Doppler transthoracic echocardiography findings EA compared controls. Results 165 (55 EAs, 110 controls) analysed (median age 29 years, male gender n=95; 58%, Chinese ethnicity n=55 EAs; 100%) Baseline characteristics between both groups comparable (Table 1). EAs had larger LV wall thickness (9.2 vs. 8.1 mm, p<0.001), cavity size (50.7 48.2 mass index (98.4 73.8 g/m2, aortic root diameter at sinus Valsalva (30.6 28.9 p<0.01), dimensions biatrial volumes 2). Similar noted after indexing body surface area. associations also persisted adjusting age. Conclusion(s) Endurance activity Singaporean was associated significant structural functional remodeling Reference described, allowing more accuracy when differentiating pathology Funding Acknowledgement Type funding None.